EGFR-HER2 inhibitor HS-10296 hydrochloride, Purity ≥98%

Synonym: 2134096-03-8; HS10296; HS 10296; EGFR-HER2 inhibitor

CAS Number: 2134096-03-8
Compound CID: 137319707

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

HS-10296 hydrochloride is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (del19 T790M), EGFR (L858R/T790M), and EGFR(T790M).

Molecular Weight

562.11

Molecular Formula

C₃₀H₃₆ClN₇O₂

Targets

EGFR (del19 T790M): 0.21 nM; EGFR (L858R/T790M): 0.29 nM; EGFR(T790M): 0.37 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

HS-10296 hydrochloride can be used to study its effect as a third-generation EGFR inhibitor in treating NSCLC.