EGFR-HER2 inhibitor Icotinib hydrochloride, Purity ≥98%

Synonym: 1204313-51-8; BPI-2009H; EGFR-HER2 inhibitor

CAS Number: 1204313-51-8
Compound CID: 44609731

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Icotinib hydrochloride is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, EGFR (L858R), EGFR(L858R)/T790M, and EGFR(L861Q).

Molecular Weight

427.88

Molecular Formula

C₂₂H₂₂ClN₃O₄

Targets

EGFR: 5 nM; EGFR (L858R); EGFR(L858R)/T790M; EGFR(L861Q)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

Icotinib hydrochloride is utilized in research focusing on its selective inhibition of EGFR tyrosine kinase in non-small cell lung cancer.