Properties
Description
Icotinib hydrochloride is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, EGFR (L858R), EGFR(L858R)/T790M, and EGFR(L861Q).
Molecular Formula
C22H22ClN3O4
Targets
EGFR: 5 nM; EGFR (L858R); EGFR(L858R)/T790M; EGFR(L861Q)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Icotinib hydrochloride is utilized in research focusing on its selective inhibition of EGFR tyrosine kinase in non-small cell lung cancer.
