Properties
Description
Icotinib, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR.
Molecular Formula
C22H21N3O4
Solubility
DMSO: 66 mg/mL (168.61 mM); Water: Insoluble; Ethanol: 6 mg/mL (15.33 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Icotinib is investigated for its role as an EGFR tyrosine kinase inhibitor in lung cancer research.
