EGFR-HER2 inhibitor Icotinib, Purity ≥98%

Synonym: 610798-31-7; BPI-2009H; EGFR-HER2 inhibitor

CAS Number: 610798-31-7
Compound CID: 22024915

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Icotinib, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR.

Molecular Weight

391.42

Molecular Formula

C₂₂H₂₁N₃O₄

Targets

EGFR: 5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 66 mg/mL (168.61 mM); Water: Insoluble; Ethanol: 6 mg/mL (15.33 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Icotinib is investigated for its role as an EGFR tyrosine kinase inhibitor in lung cancer research.