Properties
Description
Mutated EGFR-IN-2 is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (ex19del/T790M), EGFR (L858R/T790M), EGFR(L858R), and EGFRex19del.
Molecular Formula
C29H35FN8O3
Targets
EGFR (ex19del/T790M); EGFR (L858R/T790M): <1 nM; EGFR(L858R); EGFRex19del
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Mutated EGFR-IN-2 can be used to study its effect as a selective inhibitor of mutant EGFR in cancer treatment.