Properties
Description
Naquotinib mesylate is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, EGFR (L858R), EGFR (L858R)/T790M, EGFRExon 19 deletion, and EGFRExon 19 deletion/T790M.
Molecular Formula
C31H46N8O6S
Targets
EGFR: 230 nM; EGFR (L858R); EGFR (L858R)/T790M; EGFRExon 19 deletion; EGFRExon 19 deletion/T790M
Identity
Confirmed by NMR/HPLC/MS.
Applications
EGFR-HER2 inhibitor Naquotinib mesylate is a research tool for studying and inhibiting EGFR-HER2 signaling pathways, which are critical in cancer progression, particularly in lung cancers.
