EGFR-HER2 inhibitor Nazartinib mesylate, Purity ≥98%

Synonym: 1508250-72-3; EGF816 (mesylate); EGF 816; EGF-816; EGFR-HER2 inhibitor

CAS Number: 1508250-72-3
Compound CID: 91809207

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Nazartinib mesylate is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (L858/T790MR).

Molecular Weight

591.12

Molecular Formula

C₂₇H₃₅ClN₆O₅S

Targets

EGFR (L858/T790MR): 31 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Nazartinib mesylate can be used to explore its therapeutic potential as a third-generation EGFR inhibitor.

Storage

Store at -20ºC.