EGFR-HER2 inhibitor PD153035, Purity ≥98%

Synonym: 183322-45-4; PD153035 hydrochloride; N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride; PD-153035 hydrochloride; EGFR-HER2 inhibitor

MDL: MFCD01074805
CAS Number: 183322-45-4
Compound CID: 11246488

Product Size

10 mg; 25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PD153035, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR and EGFR.

Molecular Weight

396.7

Molecular Formula

C₁₆H₁₄BrN₃O₂.HCl

Targets

EGFR: 5.2 pM (Ki); EGFR: 5.2 pM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 0.46 mg/mL (1.16 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PD153035 can be used to inhibit EGFR tyrosine kinase in cancer research.

Storage

Store at -20ºC.