EGFR-HER2 inhibitor PD153035, Purity ≥98%

Synonym: 183322-45-4; PD153035 hydrochloride; N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride; PD-153035 hydrochloride; EGFR-HER2 inhibitor

MDL: MFCD01074805
CAS Number: 183322-45-4
Compound CID: 11246488

Product Size

10 mg; 25 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PD153035, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR and EGFR.

Molecular Weight

396.7

Molecular Formula

C₁₆H₁₄BrN₃O₂.HCl

Targets

EGFR: 5.2 pM (Ki); EGFR: 5.2 pM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 0.46 mg/mL (1.16 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PD153035 can be used to inhibit EGFR tyrosine kinase in cancer research.