EGFR-HER2 inhibitor PD158780, Purity ≥98%

Synonym: 171179-06-9; PD-158780; EGFR-HER2 inhibitor

CAS Number: 171179-06-9
Compound CID: 4707

Product Size

10 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PD158780 is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, ErbB2, ErbB3, and ErbB4.

Molecular Weight

330.18

Molecular Formula

C₁₄H₁₂BrN₅

Targets

EGFR: 8 μM; ErbB2: 49 nM; ErbB3: 52 nM; ErbB4: 52 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

PD158780 can be used to study its function as an EGFR tyrosine kinase inhibitor in cancer cell signaling.