Cat. No.: X24-05-ZQ632
EGFR-HER2 inhibitor PD168393, Purity ≥98%
Synonym: 194423-15-9; PD-168393; PD 168393; EGFR-HER2 inhibitor
- CAS Number: 194423-15-9
- Compound CID: 4708
Product Size
5 mg; 10 mg; 50 mg
Properties
Description
PD168393, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, FGFR, Insulin Receptor, and PDGFR.
Molecular Formula
C17H13BrN4O
Targets
EGFR: 0.70 nM; FGFR: >50 μM; Insulin Receptor: >50 μM; PDGFR: >50 μM
Solubility
DMSO: 72 mg/mL (195 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PD168393 is used to inhibit EGFR tyrosine kinase in research on cancer cell proliferation and survival pathways.
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