EGFR-HER2 inhibitor Pyrotinib dimaleate, Purity ≥98%

Synonym: 1397922-61-0; SHR-1258 dimaleate; SHR1258; SHR 1258; EGFR-HER2 inhibitor

CAS Number: 1397922-61-0
Compound CID: 72710866

Product Size

1 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Pyrotinib dimaleate, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR and HER2.

Molecular Weight

815.22

Molecular Formula

C₄₀H₃₉ClN₆O₁₁

Targets

EGFR: 13 nM; HER2: 38 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: Insoluble; Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

Pyrotinib dimaleate can be used to study its effects as a pan-ErbB inhibitor in cancer therapy.