Properties
Description
Pyrotinib dimaleate, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR and HER2.
Molecular Formula
C40H39ClN6O11
Targets
EGFR: 13 nM; HER2: 38 nM
Solubility
DMSO: Insoluble; Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Pyrotinib dimaleate can be used to study its effects as a pan-ErbB inhibitor in cancer therapy.
