EGFR-HER2 inhibitor RG14620, Purity ≥98%

Synonym: 136831-49-7; RG 14620; RG-14620; Tyrphostin RG14620; EGFR-HER2 inhibitor

CAS Number: 136831-49-7
Compound CID: 5353928

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

RG14620, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR.

Molecular Weight

275.13

Molecular Formula

C₁₄H₈Cl₂N₂

Targets

EGFR: 3 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 52 mg/mL (189 mM); Water: Insoluble; Ethanol: 6 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

RG14620 can be used to explore its role as a tyrosine kinase inhibitor in cancer research.