Properties
Description
RG14620, soluble in DMSO and ethanol and insoluble in water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR.
Molecular Formula
C14H8Cl2N2
Solubility
DMSO: 52 mg/mL (189 mM); Water: Insoluble; Ethanol: 6 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
RG14620 can be used to explore its role as a tyrosine kinase inhibitor in cancer research.