EGFR-HER2 inhibitor Tyrphostin AG-528, Purity ≥98%

Synonym: 133550-49-9; Tyrphostin B66; EGFR-HER2 inhibitor

CAS Number: 133550-49-9
Compound CID: 1838043

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Tyrphostin AG-528, soluble in DMSO, water and ethanol, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR and ErbB2.

Molecular Weight

306.32

Molecular Formula

C₁₈H₁₄N₂O₃

Targets

EGFR: 4.9 μM; ErbB2: 2.1 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 60 mg/mL (195.87 mM); Water: <1 mg/mL; Ethanol: 5 mg/mL (16.32 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Tyrphostin AG-528 can be used to study its EGFR inhibitory effects in cancer research.