EGFR-HER2 inhibitor Vandetanib trifluoroacetate, Purity ≥98%

Synonym: 338992-53-3; Zactima trifluoroacetate; ZD6474 trifluoroacetate; ZD-6474 trifluoroacetate; ZD 6474 trifluoroacetate; EGFR-HER2 inhibitor

CAS Number: 338992-53-3
Compound CID: 17973223

Product Size

50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Vandetanib trifluoroacetate is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR/HER1, VEGFR2, and VEGFR3.

Molecular Weight

589.38

Molecular Formula

C₂₄H₂₅BrF₄N₄O₄

Targets

EGFR/HER1: 500 nM; VEGFR2: 40 nM; VEGFR3: 110 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Vandetanib trifluoroacetate is used to research its dual inhibition of VEGFR and EGFR in cancer treatment.

Storage

Store at -20ºC.