Vandetanib trifluoroacetate is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR/HER1, VEGFR2, and VEGFR3.
Molecular Weight
589.38
Molecular Formula
C24H25BrF4N4O4
Targets
EGFR/HER1: 500 nM; VEGFR2: 40 nM; VEGFR3: 110 nM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Vandetanib trifluoroacetate is used to research its dual inhibition of VEGFR and EGFR in cancer treatment.
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