EGFR-HER2 inhibitor WHI-P180, Purity ≥98%

Synonym: 211555-08-7; Janex 3; WHI-P 180; EGFR-HER2 inhibitor

CAS Number: 211555-08-7
Compound CID: 5687

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

WHI-P180, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, KDR, and RET.

Molecular Weight

297.31

Molecular Formula

C₁₆H₁₅N₃O₃

Targets

EGFR: 4 μM; KDR: 66 nM; RET: 5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 51 mg/mL (171.53 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

WHI-P180 is utilized in studies targeting EGFR inhibition and its impact on cancer cell signaling.