EGFR-HER2 inhibitor WZ8040, Purity ≥98%

Synonym: WZ8040; 1214265-57-2; WZ-8040; N-(3-((5-Chloro-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)thio)phenyl)acrylamide; N-[3-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide; EGFR-HER2 inhibitor

CAS Number: 1214265-57-2
Compound CID: 44607531

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

WZ8040, soluble in DMSO and ethanol and insoluble in water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR.

Molecular Weight

481

Molecular Formula

C₂₄H₂₅ClN₆OS

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 86 mg/mL (178.79 mM); Water: Insoluble; Ethanol: 3 mg/mL (6.23 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

WZ8040 can be used to target EGFR mutations, including T790M, for research into resistance in cancer therapy.