EGFR-HER2 inhibitor WZ8040, Purity ≥98%

Synonym: WZ8040; 1214265-57-2; WZ-8040; N-(3-((5-Chloro-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)thio)phenyl)acrylamide; N-[3-[5-Chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide; EGFR-HER2 inhibitor

CAS Number: 1214265-57-2
Compound CID: 44607531

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

WZ8040, soluble in DMSO and ethanol and insoluble in water, is a potent and specific inhibitor of the tyrosine kinase activity of EGFR.

Molecular Weight

481

Molecular Formula

C₂₄H₂₅ClN₆OS

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 86 mg/mL (178.79 mM); Water: Insoluble; Ethanol: 3 mg/mL (6.23 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

WZ8040 can be used to target EGFR mutations, including T790M, for research into resistance in cancer therapy.

Storage

Store at -20ºC.