EGFR-HER2 inhibitor XL647, Purity ≥98%

Name: EGFR-HER2 inhibitor XL647, Purity ≥98%
SKU: X23-10-ZQ1051

Synonym: 874286-84-7; NCGC00390222-01; PD118203; EGFR-HER2 inhibitor

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

XL647 is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR, ErbB2, Flt-4, and KDR.

Molecular Weight

493.4

Molecular Formula

C₂₄H₂₇Cl₂FN₄O₂

Targets

EGFR: 0.3 nM; ErbB2: 16 nM; Flt-4: 8.7 nM; KDR: 1.5 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

XL647 can be used to study the inhibition of multiple receptor tyrosine kinases, including EGFR, HER2, and VEGFR2, in cancer.