Properties
Description
XL647 is a potent and specific inhibitor of the tyrosine kinase activity of EGFR. It targets EGFR, ErbB2, Flt-4, and KDR.
Molecular Formula
C24H27Cl2FN4O2
Targets
EGFR: 0.3 nM; ErbB2: 16 nM; Flt-4: 8.7 nM; KDR: 1.5 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
XL647 can be used to study the inhibition of multiple receptor tyrosine kinases, including EGFR, HER2, and VEGFR2, in cancer.
