EGFR inhibitor, Purity ≥98%

Synonym: 879127-07-8; Epidermal growth factor receptor inhibitor; EGFR-HER2 inhibitor

CAS Number: 879127-07-8
Compound CID: 9549299

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

EGFR inhibitor, soluble in DMSO, water and ethanol, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR (WT), EGFR (L858R), EGFREGFR(L861Q), and HER4.

Molecular Weight

413.4

Molecular Formula

C₂₁H₁₈F₃N₅O

Targets

EGFR (WT): 21 nM; EGFR (L858R): 63 nM; EGFREGFR(L861Q): 4 nM; HER4: 7640 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 79 mg/mL (191.09 mM); Water: <1 mg/mL; Ethanol: 2 mg/mL (4.83 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

EGFR inhibitor is a general term for compounds used to block EGFR activity in various cancer research studies.