Properties
Description
Eltrombopag, soluble in DMSO and insoluble in water and ethanol, is an agonist of the thrombopoietin (TPO) receptor. The molecular weight of the compound is 442.47, and its molecular formula is C25H22N4O4.
Molecular Formula
C25H22N4O4
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO (warmed): 22 mg/mL (49.72 mM); Water: insoluble; Ethanol: insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Eltrombopag plays a key role in enhancing signaling pathways that stimulate megakaryocyte proliferation and differentiation.