Epigenetic reader domain inhibitor Apabetalone, Purity ≥98%

Cat. No.: X24-05-ZQ415

Epigenetic reader domain inhibitor Apabetalone, Purity ≥98%

Synonym: 1044870-39-4; RVX-000222; RVX-208; Epigenetic reader domain inhibitor

  • CAS Number: 1044870-39-4
  • Compound CID: 135564749
Product Size
10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
Apabetalone, soluble in DMSO and insoluble in ethanol and water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BD2.
Molecular Weight
370.4
Molecular Formula
C20H22N2O5
Targets
BD2: 0.51 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 63 mg/mL (170.08 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Apabetalone can be used to investigate the inhibition of BET bromodomains, focusing on therapeutic potential in cardiovascular and metabolic diseases.
Storage
Store at -20ºC.
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