Epigenetic reader domain inhibitor BAY-299, Purity ≥98%

Synonym: 2080306-23-4; BAY 299; BAY299; Epigenetic reader domain inhibitor

CAS Number: 2080306-23-4
Compound CID: 122705990

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BAY-299 disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRPF1 BD, BRPF2 BD, BRPF3 BD, BRPF1 BD, and TAF1L BD2.

Molecular Weight

429.47

Molecular Formula

C₂₅H₂₃N₃O₄

Targets

BRPF1 BD: 3150 nM; BRPF2 BD: 67 nM; BRPF3 BD: 5550 nM; BRPF1 BD: 8 nM; TAF1L BD2: 106 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

BAY-299 can be utilized to explore the inhibition of BRD4, a key BET bromodomain protein, in relation to gene transcription and cancer.