Properties
Description
BI-7273, soluble in DMSO and ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals.
Molecular Formula
C20H23N3O3
Targets
BRD7: 117 nM; BRD9: 9 nM
Solubility
DMSO: 62 mg/mL (175.43 mM); Water: Insoluble; Ethanol: 62 mg/mL (175.43 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
BI-7273 can be used in research to investigate the inhibition of BET bromodomain proteins, focusing on cancer and inflammatory diseases.