Epigenetic reader domain inhibitor BRD4 inhibitor-10, Purity ≥98%

Synonym: 1660117-38-3; BRD4 Inhibitor-10; (S)-2,4-Dimethyl-6-(1-(1-phenylethyl)-6-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]pyridin-2-yl)pyridazin-3(2H)-one; 2,4-Dimethyl-6-[6-(oxan-4-yl)-1-[(1S)-1-phenylethyl]imidazo[4,5-c]pyridin-2-yl]pyridazin-3-one; BI 894999; Epigenetic reader domain inhibitor

CAS Number: 1660117-38-3
Compound CID: 90647162

Product Size

1 mg; 5 mg; 10 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BRD4 inhibitor-10, soluble in DMSO and ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD4-BD1.

Molecular Weight

429.51

Molecular Formula

C₂₅H₂₇N₅O₂

Targets

BRD4-BD1: 8 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 83 mg/mL (193.24 mM); Water: Insoluble; Ethanol: 83 mg/mL (193.24 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

BRD4 inhibitor-10 can be used to study the role of BRD4 in transcriptional regulation and cancer.

Storage

Store at -20ºC.