Properties
Description
C646, soluble in DMSO and insoluble in ethanol and water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets p300/CBP.
Molecular Formula
C24H19N3O6
Targets
p300/CBP: 400 nM (Ki)
Solubility
DMSO: 13 mg/mL (29.18 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
C646 can be used to study the inhibition of p300/CBP histone acetyltransferase in gene expression and cancer.