Properties
Description
GS-626510 disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BD1, BD2, BRD2, BRD3, and BRD4.
Molecular Formula
C25H22N4O
Targets
BD1: 83 nM; BD2: 78 nM; BRD2: 0.59-2.5 nM (Kd); BRD3: 0.65-0.66 nM (Kd); BRD4: 1.3-3.2 nM (Kd)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
GS-626510 can be used in research focused on inhibiting the bromodomain-containing protein 4 (BRD4) in diseases like cancer.
