Properties
Description
GSK 1210151A, soluble in DMSO and ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD2, BRD3, and BRD4.
Molecular Formula
C23H21N5O3
Targets
BRD2: 0.5 μM; BRD3: 0.25 μM; BRD4: 0.79 μM
Solubility
DMSO: Insoluble; Water: Insoluble; Ethanol: 27 mg/mL (64.99 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
GSK 1210151A can be used to investigate the effects of BET inhibition in various diseases, including cancer.
