Epigenetic reader domain inhibitor GSK 525762A, Purity ≥98%

Synonym: 1260907-17-2; GSK-525762A; GSK525762A; I-BET-762; Epigenetic reader domain inhibitor

CAS Number: 1260907-17-2
Compound CID: 46943432

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK 525762A, soluble in DMSO and warmed ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BET proteins.

Molecular Weight

423.9

Molecular Formula

C₂₂H₂₂ClN₅O₂

Targets

BET proteins: 35 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 72 mg/mL (169.84 mM); Water: Insoluble; Warmed ethanol: 36 mg/mL (84.92 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GSK 525762A can be used to study the therapeutic potential of BET bromodomain inhibition in cancer and other diseases.

Storage

Store at -20ºC.