Epigenetic reader domain inhibitor GSK1324726A, Purity ≥98%

Synonym: 1300031-52-0; I-BET726; GSK 1324726A; GSK-1324726A; I-BET 726; I-BET726; Epigenetic reader domain inhibitor

CAS Number: 1300031-52-0
Compound CID: 52912222

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

GSK1324726A, soluble in DMSO and ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD2, BRD3, and BRD4.

Molecular Weight

434.91

Molecular Formula

C₂₅H₂₃ClN₂O₃

Targets

BRD2: 41 nM; BRD3: 31 nM; BRD4: 22 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 77 mg/mL (177.05 mM); Water: Insoluble; Ethanol: 77 mg/mL (177.05 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

GSK1324726A can be used to research the therapeutic implications of BET bromodomain inhibition in oncology.

Storage

Store at -20ºC.