Epigenetic reader domain inhibitor HJB-97, Purity ≥98%

Synonym: 2093391-24-1; HJB 97; HJB97; Epigenetic reader domain inhibitor

CAS Number: 2093391-24-1
Compound CID: 135397673

Product Size

5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

HJB-97 disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD2-BD1, BRD2 BD1, BRD2 BD2, BRD2 BD2, BRD3 BD1, BRD3 BD1, BRD3 BD2, BRD3 BD2, BRD4 BD1, BRD4 BD1, and BRD4 BD2.

Molecular Weight

500.56

Molecular Formula

C₂₆H₂₈N₈O₃

Targets

BRD2-BD1: 0.9±0.2 nM (Ki); BRD2 BD1: 3.1±0.7 nM; BRD2 BD2: 0.27±0.09 nM (Ki); BRD2 BD2: 3.9±0.5 nM; BRD3 BD1: 0.18±0.01 nM (Ki); BRD3 BD1: 0.18±0.01 nM (Ki); BRD3 BD2: 0.21±0.03 nM (Ki); BRD3 BD2: 1.9±0.4 nM; BRD4 BD1: 0.5±0.2 nM (Ki); BRD4 BD1: 7.0±0.6 nM; BRD4 BD2: 1.0±0.1 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

HJB-97 can be used to study molecular mechanisms related to BET (Bromodomain and Extra-Terminal) family proteins.

Storage

Store at -20ºC.