Epigenetic reader domain inhibitor I-BRD9, Purity ≥98%

Synonym: 1714146-59-4; GSK602; Epigenetic reader domain inhibitor

CAS Number: 1714146-59-4
Compound CID: 91668541

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

I-BRD9, soluble in DMSO and insoluble in ethanol and water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD4 and BRD9.

Molecular Weight

497.55

Molecular Formula

C₂₂H₂₂F₃N₃O₃S₂

Targets

BRD4: 5.3 (pIC₅₀); BRD9: 7.3(pIC₅₀)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 94 mg/mL (188.92 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

I-BRD9 is used to investigate the role of the BRD9 bromodomain in gene regulation and chromatin remodeling.

Storage

Store at -20ºC.