Properties
Description
(+)-JQ1, soluble in warmed DMSO and ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals.
Molecular Formula
C23H25ClN4O2S
Solubility
Warmed DMSO: 90 mg/mL (196.93 mM); Water: Insoluble; Ethanol: 90 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
(+)-JQ1 can be utilized to study the inhibition of the BET family of bromodomain proteins, particularly their role in cancer and inflammation through epigenetic regulation.
