Properties
Description
MS402 disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD2-BD1, BRD2-BD2, BRD3-BD1, BRD3-BD2, BRD4-BD1, and BRD4-BD2.
Molecular Formula
C20H19ClN2O3
Targets
BRD2-BD1: 83 nM (Ki); BRD2-BD2: 240 nM (Ki); BRD3-BD1: 110 nM (Ki); BRD3-BD2: 200 nM (Ki); BRD4-BD1: 77 nM (Ki); BRD4-BD2: 718 nM (Ki)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
MS402 serves as a research tool to explore the involvement of bromodomains in disease and gene expression patterns.
