Epigenetic reader domain inhibitor MS436, Purity ≥98%

Synonym: 1395084-25-9; MS 436; MS-436; Epigenetic reader domain inhibitor

CAS Number: 1395084-25-9
Compound CID: 135566899

Product Size

5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MS436, soluble in DMSO and warmed ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRD4 (1) and BRD4 (2).

Molecular Weight

383.42

Molecular Formula

C₁₈H₁₇N₅O₃S

Targets

BRD4 (1): <0.085 μM (Ki); BRD4 (2): 0.34 μM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 50 mg/mL (130.4 mM); Water: Insoluble; Warmed ethanol: 1 mg/mL (2.6 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

MS436 is utilized in research targeting BET bromodomains to modulate gene transcription.

Storage

Store at -20ºC.