Properties
Description
OTX015, soluble in DMSO and ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRDs.
Molecular Formula
C25H22ClN5O2S
Targets
BRDs: 10-19 nM (EC50)
Solubility
DMSO: 89 mg/mL (180.9 mM); Water: Insoluble; Ethanol: 89 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
OTX015 is used to study BET bromodomain inhibitors in pre-clinical cancer models.
