Epigenetic reader domain inhibitor PF-4, Purity ≥98%

Synonym: 900305-37-5; PF4; PF 4; Epigenetic reader domain inhibitor

CAS Number: 900305-37-5
Compound CID: 40642506

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PF-4, soluble in warmed DMSO and warmed ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets BRPF1, BRPF2, and BRPF3.

Molecular Weight

380.44

Molecular Formula

C₂₁H₂₄N₄O₃

Targets

BRPF1: 80 μM; BRPF2: 7.9 μM; BRPF3: >10 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 17 mg/mL (44.68 mM); Water: Insoluble; Warmed ethanol: 5 mg/mL (13.14 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

PF-4 is employed to explore the therapeutic effects of BET inhibition in cancer research.

Storage

Store at -20ºC.