Properties
Description
UNC 669, soluble in DMSO and ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets L3MBTL1, L3MBTL3, and L3MBTL4.
Molecular Formula
C15H20BrN3O
Targets
L3MBTL1: 6 μM; L3MBTL3: 35 μM; L3MBTL4: 69 μM
Solubility
DMSO: 10 mg/mL (29.56 mM); Water: Insoluble; Ethanol: 62 mg/mL (183.3 mM)
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
UNC 669 is employed in the study of the L3MBTL1 methyl-lysine reader domain and its biological significance.