Epigenetic reader domain inhibitor UNC1215, Purity ≥98%

Synonym: 1415800-43-9; UNC 1215; UNC-1215; Epigenetic reader domain inhibitor

CAS Number: 1415800-43-9
Compound CID: 57339144

Product Size

10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

UNC1215, soluble in DMSO and ethanol and insoluble in water, disrupts the function of proteins that recognize and bind specific epigenetic marks, affecting the interpretation of epigenetic signals. It targets L3MBTL3, L3MBTL3, and L3MBTL3- D274A.

Molecular Weight

529.72

Molecular Formula

C₃₂H₄₃N₅O₂

Targets

L3MBTL3: 40 nM; L3MBTL3: 120 nM (Kd); L3MBTL3- D274A: 3.5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 92 mg/mL (173.67 mM); Water: Insoluble; Ethanol: 92 mg/mL (173.67 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

UNC1215 is used to investigate the role of the L3MBTL3 methyl-lysine reader domain in gene regulation.

Storage

Store at -20ºC.