Epoxymicheliolide is a novelguaiane-type sesquiterpene lactone that displays significant inhibitory effects on F‑κB/COX‑2 signaling pathways by targeting leucine 281 and leucine 25 in IKKβ in renal cell carcinoma.
Molecular Formula
C15H20O4
Form
Powder
Purity
≥98%, determined by HPLC.
Applications
Epoxymicheliolide is useful for its ability to reduce the risk of dextran sulfate sodium-induced colitis in mice.
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