ERK inhibitor MK-8353, Purity ≥98%

Synonym: MK-8353; 1184173-73-6; SCH900353; MK8353; SCH-900353; CHEMBL4213970; (3S)-3-Methylsulfanyl-1-[2-[4-[4-(1-methyl-1,2,4-triazol-3-yl)phenyl]-3,6-dihydro-2H-pyridin-1-yl]-2-oxoethyl]-N-[3-(6-propan-2-yloxypyridin-3-yl)-1H-indazol-5-yl]pyrrolidine-3-carboxamide; ERK inhibitor

CAS Number: 1184173-73-6
Compound CID: 58282870

Product Size

2 mg; 5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MK-8353, soluble in DMSO and insoluble in ethanol and water, exhibits potent inhibition of ERK kinase.

Molecular Weight

691.84

Molecular Formula

C₃₇H₄₁N₉O₃S

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 45 mg/mL (65.04 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

MK-8353 can be employed to investigate ERK pathway inhibition and its effects on cancer cell proliferation.