Erythromycin Lactobionate Analysis Service

Sincerity and Honesty in Service Related to Erythromycin Lactobionate Analysis at CD BioGlyco

CD BioGlyco offers complete analytical services for a wide range of Pharmaceuticals. Erythromycin lactobionate is a macrolide antibiotic which is the lactobionate of erythromycin. We provide a high-quality erythromycin lactobionate analysis service to support our client's research needs regarding its pharmacology and more. Our analysis service is focused on erythromycin lactobionate for injection (powder, sterile crystals, or sterile lyophilized product of erythromycin lactobionate).

Our analytical methods:
We have extensive experience in Pharmaceutical and Biological Analysis with a variety of analytical methods.
- High-performance liquid chromatography (HPLC): It is widely used for the quantitative analysis of macrolide antibiotics such as erythromycin lactobionate. It has the advantages of high selectivity, simple analysis, high sensitivity, and high efficiency.
- Spectrophotometry: Spectrophotometry is one of the commonly used methods for the analysis of erythromycin lactobionate, often used with HPLC and so on.
- Gas chromatography: It analyzes compounds quantitatively, and has the advantages of fast analysis, high efficiency, and simple operation.
- Other methods (Ultraviolet-visible (UV–visible) spectrophotometry, etc)
Erythromycin lactobionate analytical item:
- Character observation
- Sample identification
- pH: The pH value of the sample should be 6.0-7.5.
- Clarity and color of the solution
- Erythromycin A: HPLC
- Detection of erythromycin B, Erythromycin C, and related substances: HPLC
- Moisture
- Visible foreign matter
- Insoluble particles
- Bacterial endotoxins
- Sterility testing
- Detection of erythromycin content

Fig.1 Erythromycin lactobionate analysis service. (CD BioGlyco)

Publication Data

Technology: HPLC

Journal: International Scholarly Research Notices

IF: 1.116

Published: 2012

Results: The present study presents several effective methods for analyzing drugs like erythromycin lactobionate, such as HPLC, spectrophotometric techniques, etc., and describes an HPLC chromatographic condition for the detection of erythromycin lactobionate. From the comparison with different methods, it is clear that HPLC is a valuable tool for quantitative analysis of erythromycin lactobionate.

Tab.1 Reported chromatographic conditions that are used for the analysis of drugs such as erythromycin lactobionate. (Bekele & Gebeyehu, 2012)

Analyte	Stationary phase/column temp	Mobile phase/flow rate	Detection
Erythromycin lactobionate (i.v) and erythromycin tablet	4.6 mm × 25 cm, 8–10 μm, L21/70	3.5% K₂HPO₄ (pH = 9): H₂O: 2-methyl propanol: acetonitrile (50: 755 : 165: 30)/1 mL/min	UV-Vis at 215 nm
Erythromycin raw material	4.6 mm × 25 cm, L21/70	0.2 M K₂HPO₄ (pH = 9): H₂O: tertiarybutyl alcohol: acetonitrile (50: 755: 165: 30)/2 mL/min	UV-Vis at 215 nm
Clarithromycin (raw material and tablet)	4.6 mm × 15 cm, L₁/50	CH₃OH: .067 M KH₂PO₄ (pH = 4) (65: 35)/1 mL/min	UV-Vis at 210 nm

Highlights of Us

Our analytical techniques meet all the needs of erythromycin lactobionate research, including physicochemical analysis, impurity analysis, and many other testing methods.
Our analytical methods have high separation efficiency, assay sensitivity, selectivity, and precision.
We are equipped with a professional testing team to complete erythromycin lactobionate analysis and deliver results efficiently.

CD BioGlyco helps clients solve bottlenecks encountered in pharmaceutical research through a variety of pharmaceutical analytical methods. Welcome to contact us for more information about erythromycin lactobionate. Our researchers specializing in pharmaceutical analysis will get back to you as soon as possible.

Reference

Bekele, L.K.; Gebeyehu, G.G. Application of different analytical techniques and microbiological assays for the analysis of macrolide antibiotics from pharmaceutical dosage forms and biological matrices. International Scholarly Research Notices. 2012, 1-17.

This service is for Research Use Only, not intended for any clinical use.