Properties
Description
ESI-09, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets EPAC1, and EPAC2.
Molecular Formula
C16H15ClN4O2
Targets
EPAC1: 3.2 μM; EPAC2: 1.4 μM
Solubility
DMSO: 63 mg/mL (190.46 mM); Water: insoluble; Ethanol: 19 mg/mL (57.44 mM)
Applications
ESI-09 can be studied for its effect on enhancing the reprogramming of somatic cells into induced pluripotent stem cells (iPSCs).