Properties
Description
GW9508, soluble in DMSO and ethanol and insoluble in water, prevents the growth of cancer cells that depend on estrogen for proliferation. It targets GPR120 and GPR40.
Molecular Formula
C22H21NO3
Targets
GPR120: 5.46 (pEC50); GPR40: 7.32 (pEC50)
Solubility
DMSO: 63 mg/mL (181.34 mM); Water: Insoluble; Ethanol: 63 mg/mL (181.34 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GW9508 is used in studies focused on inhibiting estrogen receptor signaling pathways with implications in cancer and metabolic diseases.