Estrogen receptor inhibitor H3B-5942, Purity ≥98%

Synonym: 2052128-15-9; Estrogen receptor inhibitor; H3B5942; H3B 5942

CAS Number: 2052128-15-9
Compound CID: 124091011

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

H3B-5942, soluble in DMSO and ethanol and insoluble in water, prevents the growth of cancer cells that depend on estrogen for proliferation. It targets ERαWT and ERαY537S.

Molecular Weight

494.63

Molecular Formula

C₃₁H₃₄N₄O₂

Targets

ERαWT: 1 nM (Ki); ERαY537S: 0.41 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 88 mg/mL (177.9 mM); Water: Insoluble; Ethanol: 12 mg/mL (24.26 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

H3B-5942 is employed to investigate selective estrogen receptor degradation, providing insight into novel cancer therapeutic strategies.