Cat. No.: X22-05-ZQ129
Etoposide
Synonym: 33419-42-0; etoposide; VePesid; (5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-Dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-Hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
- MDL: MFCD00869325
- CAS Number: 33419-42-0
- Compound CID: 36462
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Properties
Description
Etoposide is a semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double-stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle. This product can be used for research in the fields of medicine and pharmacy.
Molecular Formula
C29H32O13
Purity
≥98%, determined by HPLC.
Identity
Confirmed by MS and NMR.
Stability
The product is stable for two years when stored at the recommended temperature.
Applications
Etoposide can be used for research in the fields of medicine and pharmacy.
Storage
Store at 4°C. Protect from light.
Safety Information
Personal Protective Equipment
Gloves, eyeshields, N95 mask
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