EW-7197

Synonym: 1352608-82-2; EW7197; Vactosertib

CAS Number: 1352608-82-2
PubChem CID: 54766013

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

EW-7197 (vactosertib), soluble in DMSO and ethanol and insoluble in water, inhibits the activity of protein-tyrosine kinases that play a critical role in cell signaling and regulation. It targets ALK1, ALK4, ALK2, ALK3, ALK5, and ALK6.

Molecular Weight

399.42

Molecular Formula

C₂₂H₁₈FN₇

Targets

ALK1: >10 μM; ALK4: 13 nM; ALK2: >10 μM; ALK3: >10 μM; ALK5: 11 nM; ALK6: >10 μM

Form

Lyophilized powder

Purity

>98%

Solubility

DMSO: 77 mg/mL (192.77 mM); Water: insoluble; Ethanol: 42 mg/mL (105.15 mM)

Applications

EW-7197 (vactosertib) can be used for its ability to influence the rate and quality of wound healing.