FAAH inhibitor, PF-04457845, Purity ≥98%

Synonym: 1020315-31-4; PF 04457845; PF04457845; Redafamdastat; N-pyridazin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methylidene]piperidine-1-carboxamide; 1-Piperidinecarboxamide, N-3-pyridazinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methylene]-; N-Pyridazin-3-yl-4-[[3-[5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]methylidene]piperidine-1-carboxamide; FAAH inhibitor

MDL: MFCD18782721
CAS Number: 1020315-31-4
Compound CID: 24771824

Product Size

5 mg; 10 mg; 20 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PF-04457845, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting FAAH. The molecular weight of the compound is 455.43, and its molecular formula is C₂₃H₂₀F₃N₅O₂.

Molecular Weight

455.43

Molecular Formula

C₂₃H₂₀F₃N₅O₂

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 90 mg/mL (197.61 mM); Water: insoluble; Ethanol: 4 mg/mL (8.78 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

PF-04457845 can be studied extensively for its potential therapeutic applications in the treatment of asthma and allergic rhinitis by blocking the effects of leukotrienes, which are involved in inflammatory and allergic responses.