Factor Xa inhibitor, Apixaban, Purity ≥98%

Synonym: 503612-47-3; Eliquis; BMS-562247-01; BMS-562247; BMS 562247-01; 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide; Factor Xa inhibitor

MDL: MFCD11977295
CAS Number: 503612-47-3
Compound CID: 10182969

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Apixaban, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting factor Xa. The molecular weight of the compound is 459.5, and its molecular formula is C₂₅H₂₅N₅O₄. It targets the Factor Xa (human) (Cell-free assay) and Factor Xa (rabbit) (Cell-free assay).

Molecular Weight

459.5

Molecular Formula

C₂₅H₂₅N₅O₄

Targets

Factor Xa (human) (Cell-free assay)

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 17 mg/mL (36.99 mM); Water: insoluble; Ethanol: insoluble; In vivo: 30% PEG 400 + 0.5% Tween 80 + 5% Propylene glycol, 28 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

Apixaban can be studied extensively for its potential therapeutic applications in the treatment of deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke in patients with non-valvular atrial fibrillation (AF).