Properties
Description
Rivaroxaban, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting factor Xa. The molecular weight of the compound is 435.9, and its molecular formula is C19H18ClN3O5S. It targets the Factor Xa (Cell-free assay) and Prothrombinase (Cell-free assay).
Molecular Formula
C19H18ClN3O5S
Targets
Factor Xa (Cell-free assay)
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 83 mg/mL (190.41 mM); Water: insoluble; Ethanol: insoluble; In vivo: 0.5% methylcellulose + 0.2% Tween 80, 4 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Rivaroxaban can be studied extensively for its potential therapeutic applications in the treatment of deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke in patients with non-valvular atrial fibrillation (AF).
