FAK inhibitor PF-03814735, Purity ≥98%

Synonym: PF-03814735; 942487-16-3; PF 03814735; N-(2-((1S,4R)-6-((4-(Cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl)-2-oxoethyl)acetamide; CHEMBL4289017; PF 3814735; PF-3814735; FAK inhibitor

CAS Number: 942487-16-3
Compound CID: 51346455

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PF-03814735 is a FAK inhibitor that is used to block angiogenesis in diseases such as cancer. It targets Aurora A, Aurora B, FAK, FLT1, and TrkA.

Molecular Weight

474.48

Molecular Formula

C₂₃H₂₅F₃N₆O₂

Targets

Aurora A: 0.8 nM; Aurora B: 5 nM; FAK: 22 nM; FLT1: 10 nM; TrkA: 30 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

PF-03814735 can be used to investigate the dual inhibition of Aurora kinases and its effects on tumor cells.