Cat. No.: X23-10-ZQ479
FAK inhibitor PF-03814735, Purity ≥98%
Synonym: PF-03814735; 942487-16-3; PF 03814735; N-(2-((1S,4R)-6-((4-(Cyclobutylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-1,2,3,4-tetrahydro-1,4-epiminonaphthalen-9-yl)-2-oxoethyl)acetamide; CHEMBL4289017; PF 3814735; PF-3814735; FAK inhibitor
- CAS Number: 942487-16-3
- Compound CID: 51346455
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
PF-03814735 is a FAK inhibitor that is used to block angiogenesis in diseases such as cancer. It targets Aurora A, Aurora B, FAK, FLT1, and TrkA.
Molecular Formula
C23H25F3N6O2
Targets
Aurora A: 0.8 nM; Aurora B: 5 nM; FAK: 22 nM; FLT1: 10 nM; TrkA: 30 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
PF-03814735 can be used to investigate the dual inhibition of Aurora kinases and its effects on tumor cells.
