FAK inhibitor PF 431396, Purity ≥98%

Synonym: 717906-29-1; FAK inhibitor; PF-431396

MDL: MFCD16038300
CAS Number: 717906-29-1
Compound CID: 11598628

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PF 431396, soluble in DMSO and insoluble in ethanol and water, is a FAK inhibitor that is used to block angiogenesis in diseases such as cancer. It targets FAK and PYK2.

Molecular Weight

506.5

Molecular Formula

C₂₂H₂₁F₃N₆O₃S

Targets

FAK: 2 nM; PYK2: 11 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 94 mg/mL (185.58 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PF 431396 is used to investigate and inhibit focal adhesion kinase (FAK), which plays a crucial role in processes involving cell adhesion, migration, and tumor cell survival.