Farnesyl transferase inhibitor, FTI-277 HCl, Purity ≥98%

Synonym: 180977-34-8; FTI 277; FTI277; Methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoate; hydrochloride; Farnesyl transferase inhibitor

CAS Number: 180977-34-8
Compound CID: 88309922

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

FTI-277 HCl, soluble in DMSO, water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting farnesyl transferase. The molecular weight of the compound is 484.07, and its molecular formula is C₂₂H₃₀ClN₃O₃S₂. It targets the FTase and GGTase I.

Molecular Weight

484.07

Molecular Formula

C₂₂H₃₀ClN₃O₃S₂

Targets

FTase

Form

Lyophilized powder

Purity

≥98%

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 90 mg/mL (185.92 mM; Water: 16 mg/mL (33.04 mM); Ethanol (warmed): 13 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

FTI-277 HCl can be used for its antitumor activity.